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11 Αυγ 2024 · Methylprednisolone is an FDA-approved medication used for managing and treating various conditions, including allergic reactions, arthritis, asthma exacerbations, long-term asthma maintenance, and acute exacerbations of multiple sclerosis.
23 Οκτ 2021 · Abstract. The temporal variations in the pharmacokinetics and pharmacodynamics of methylprednisolone at 8 am versus 4 pm were investigated in six healthy male volunteers. Subjects completed three phases: no drug administration, 20 mg intravenous methylprednisolone at 8 am, and the same dose at 4 pm. Methylprednisolone clearance was 28% greater ...
11 Αυγ 2024 · Methylprednisolone is an FDA-approved medication used for managing and treating various conditions, including allergic reactions, arthritis, asthma exacerbations, long-term asthma maintenance, and acute exacerbations of multiple sclerosis.
High-dose oral methylprednisolone for the treatment of multiple sclerosis relapses: cost-minimisation analysis and patient’s satisfaction. Ana María Horta-Hernández. 1 Department of Pharmacy, Hospital General Universitario de Guadalajara, Guadalajara, Spain. Find articles by Ana María Horta-Hernández. 1, Begoña Esaclera-Izquierdo.
Pulse IV methylprednisolone therapy is the intermittent administration of supraphysiological quantities of the drug to enhance its therapeutic effects while reducing its toxic effects. 1 A typical pulse regimen ranges from 500 to 1000 mg IV daily for 2–4 consecutive days. 1,2 It has been suggested that methylprednisolone may cause an acute incre...
Methylprednisolone☆ Brian L. Furman, in Reference Module in Biomedical Sciences, 2019. Introduction. Methylprednisolone is a synthetic glucocorticoid used to achieve prompt suppression of inflammation.
1 Αυγ 2017 · Study treatment consisted of 0.6 to 0.8 mg/kg/d of oral methylprednisolone or matching placebo (rounded to the nearest 4 mg and with a maximal dose of 48 mg/d) for 2 months, then tapered by 8 mg/d each month, with a total treatment period of 6 to 8 months.