Αποτελέσματα Αναζήτησης
11 Ιαν 2024 · Along with the successful COVID mRNA vaccines, the first DNA vaccine for human use, the Indian ZyCovD vaccine against SARS-CoV-2, was approved in 2021. In the current review, we first give an overview of the DNA vaccine focusing on the science, including adjuvants and delivery methods.
1 Ιουλ 2024 · A direct comparison between the trials of DNA and mRNA vaccines clearly points out that mRNA is currently more favorable than DNA – almost all nucleic acid vaccine trials that are in phase 3 are based on mRNA instead of DNA, which indicates better results from earlier phase mRNA trials.
23 Δεκ 2020 · RNA vaccines encode the antigen of interest in messenger RNA (mRNA) or self-amplifying RNA (saRNA) – molecular templates used by cellular factories to produce proteins. Because of its transitory nature, there is zero risk of it integrating with our own genetic material.
4 Οκτ 2024 · mRNA vaccines are newcomers in the field of vaccinology. Decades of work have now addressed fundamental hurdles of in vitro-transcribed (IVT) mRNA, including its highly inflammatory nature and...
12 Ιαν 2018 · This Review provides a detailed overview of mRNA vaccines and considers future directions and challenges in advancing this promising vaccine platform to widespread therapeutic use.
25 Αυγ 2021 · Here, Whitehead and colleagues review the principles of mRNA vaccine design, synthesis and delivery, assessing recent progress and key issues in the development of mRNA vaccines for a range...
12 Ιουν 2024 · In this review article, we focus mainly on mRNA, recent advances in its stability when used as a vaccine, and technologies adopted to produce mRNA vaccines, for example, SARS-CoV-2 or COVID-19 vaccines.
