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  1. 11 Ιαν 2024 · Gene vaccines work by harnessing advances in biochemistry, molecular biology, genetics and chemistry to deliver selected portions of the deoxyribonucleic acid (DNA), or messenger ribonucleic acid (mRNA), of the pathogen of interest.

  2. 4 Οκτ 2024 · A deeper understanding of the mechanisms of action of mRNA vaccines, application of novel technologies enabling rational antigen design, and innovative vaccine delivery strategies and...

  3. 1 Ιουλ 2024 · Nucleic acid technology has revolutionized vaccine development, enabling rapid design and production of RNA and DNA vaccines for prevention and treatment of diseases. The successful deployment of mRNA and plasmid DNA vaccines against COVID-19 has further validated the technology.

  4. 23 Δεκ 2020 · RNA vaccines encode the antigen of interest in messenger RNA (mRNA) or self-amplifying RNA (saRNA) – molecular templates used by cellular factories to produce proteins. Because of its transitory nature, there is zero risk of it integrating with our own genetic material.

  5. Section 12.2: Structure and Function of DNA. Nucleic acids are composed of nucleotides, each of which contains a pentose sugar, a phosphate group, and a nitrogenous base. Deoxyribonucleotides within DNA contain deoxyribose as the pentose sugar. DNA contains the pyrimidines cytosine and thymine, and the purines adenine and guanine.

  6. molecularmedicine.umc.edu › articles › the-differences-between-mrna-and-dna-vaccinesThe Differences Between mRNA and DNA Vaccines

    DNA and messenger RNA (mRNA) vaccines do not require the use of a live infectious agent such as a bacteria or virus, have been shown to stimulate disease-fighting responses in T-cells and B-cells, and are more stable, less costly and easier to produce in mass quantities than traditional vaccines.

  7. 25 Αυγ 2021 · This study reports the synthesis of SM-102 (Lipid 8); the ionizable lipid used in Moderna’s SARS-CoV-2 vaccine candidate mRNA-1273.

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