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21 Αυγ 2024 · Neutropenia is a common chemotherapy-associated adverse event (AE) in dogs and a significant cause of decreased relative dose intensity. Dose reductions (DRs) and treatment delays (TDs) are frequently applied to decrease the risk of further neutropenic events (NEs) and AEs, but there is no standardised approach.
The median survival times of dogs in the neutropenia and no neutropenia groups were 952 and 282 days, respectively (P <0.01). Dogs with lymphoma that had chemotherapy-induced neutropenia exhibited significantly increased remission and survival times compared with dogs without neutropenia.
22 Αυγ 2024 · Neutropenia is a common chemotherapy-associated adverse event (AE) in dogs and a significant cause of decreased relative dose intensity. Dose reductions (DRs) and treatment delays (TDs) are...
3 Ιουλ 2020 · Decreased neutrophil function following administration of chemotherapy has been reported in dogs with lymphoma. The first objective of our study was to determine if neutrophil oxidative burst and phagocytic activity are affected by chemotherapy 7 to 10 days following initiation of treatment in dogs with lymphoma and non-lymphoma malignancies.
Neutropenia is a common chemotherapy-associated adverse event (AE) in dogs and a significant cause of decreased relative dose intensity. Dose reductions (DRs) and treatment delays (TDs) are frequently applied to decrease the risk of further neutropenic events (NEs) and AEs, but there is no standardised approach.
1 Αυγ 2009 · If the patient becomes clinically ill or the temperature exceeds 103°C, veterinary care should be sought and hospitalization may be required. Afebrile patients with mild neutropenia (>1000/μL) generally require no treatment. Managing Category II Chemotherapy-induced Neutropenia
The risk for neutropenic sepsis is less than 5% in veterinary patients, but because dogs and cats may hide clinical signs, the condition may be quite advanced when first recognized and requires prompt veterinary intervention. Timely treatment can make the difference between life and death.
