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Lung function encompasses airway flow, volumes and capacities, and oxygenation. The anatomic and physiologic continuity of the lungs with the heart and vessels intuitively suggests that impairments in any component of lung function may impact cardiovascular health.
15 Ιουν 2021 · Right ventricular dysfunction is a hallmark of advanced pulmonary vascular, lung parenchymal, and left heart disease, yet the underlying mechanisms that govern (mal)adaptation remain incompletely characterized.
18 Μαρ 2008 · Effects of volume and/or pressure overload secondary to congenital heart disease (tetralogy of Fallot or pulmonary stenosis) on right ventricular function using cardiovascular magnetic resonance and B-type natriuretic peptide levels.
18 Δεκ 2007 · The hypoxic pulmonary vasoconstrictor response is an important adaptive mechanism in human physiology, shunting blood away from hypoxic regions toward better-ventilated areas of the lung, thus improving ventilation-perfusion matching within the lung.
The normal RV is thin-walled (~3–5 mm) and highly compliant when compared with its left-sided counterpart. 12 Under resting conditions, RV afterload (pulmonary arterial pressure) is low and deoxygenated blood is transited into the lungs at minimal cost to overall myocardial oxygen demand.
17 Ιουλ 2023 · Right heart failure is most commonly a result of left ventricular failure via volume and pressure overload. Clinically, patients will present with signs and symptoms of chest discomfort, breathlessness, palpitations, and body swelling.
Abstract. There is increasing recognition of the crucial role of the right ventricle (RV) in determining functional status and prognosis in multiple conditions. The normal RV is anatomically and functionally different from the left ventricle, which precludes direct extrapolation of our knowledge of left-sided physiopathology to the right heart.
