Αποτελέσματα Αναζήτησης
It seeks to better serve patients and families through guidance on how to provide as close to a normal, healthy diet as possible while maximizing dietary management of their IEM. Most recently, the group has developed guidelines for various IEM using formalized evidence-based literature reviews and consensus processes.
Cardiopulmonary failure and acute cerebral events have been described as the leading cause of mortality in adult mitochondrial patients. 15 Patients with mitochondrial disease are more likely to have underlying myopathy, immobility, dysphagia, chronic intestinal pseudo-obstruction (CIPO), cardiomyopathy, and cardiac arrhythmias including Wolf ...
12 Ιουν 2024 · Mitochondrial disease results from failure of mitochondria to function properly. This can lead to less energy, cell injury and cell death. The most common organs that may experience damage are the brain, heart, liver, muscles, kidneys and the endocrine system.
General Guidelines . 4-6 small meals a day . include complex carbohydrate and protein at each meal. maintain a healthy weight.
Diet: Dietary needs are extremely variable from patient to patient with mitochondrial myopathies. It is required to evaluate a patient’s nutritional deficiencies. Potential therapies include supplementing caloric intake, enteral feeding, increasing the frequency of meals, limited fasting, and parenteral nutrition ( Parikh et al., 2009 ).
Certain dietary supplements may be of value in treating PMDs because, as nutrients and metabolic cofactors, they help increase mitochondrial ATP production, bypass a cellular defect (e.g., a deficiency in the activity of complexes I, II, or III in the ETC), or remove toxic metabolites [9, 14].
27 Ιουλ 2017 · Consensus-based recommendations are provided for the routine care and management of patients with primary genetic mitochondrial disease.
