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12 Ιουν 2024 · Depending on the specific type of mitochondrial disease, common symptoms include muscle weakness, imbalance, gastrointestinal problems, poor growth, liver disease, heart disease, diabetes, visual and hearing issues, lactic acidosis, and developmental delays. Mitochondrial disease may be inherited.
30 Αυγ 2024 · Treatment is based on how severe your symptoms are and whether you often have bouts when symptoms get worse. These bouts are called exacerbations. Effective therapy can control symptoms, slow how fast the condition worsens, lower the risk of complications and improve your ability to lead an active life.
The GOLD 2018 document states that the treatment goals for COPD are symptom reduction (including improved exercise capacity and overall health status) as well as risk reduction for adverse outcomes (symptom progression, exacerbations, and mortality).
This review is aimed at a general medical and neurologist readership and provides a clinical approach to the recognition, investigation, and treatment of mitochondrial myopathies. Emphasis is placed on practical management considerations while including some recent updates in the field.
30 Αυγ 2024 · Although COPD is a condition that can get worse over time, COPD is treatable. With proper management, most people with COPD can control symptoms and improve their quality of life. Proper management also can lower the risk of other conditions linked to COPD, such as heart disease and lung cancer.
Mitochondrial dysfunction is featured by increased generation of mitochondrial reactive oxygen species, reduced mitochondrial membrane potential, mitochondrial calcium imbalance, mitochondrial DNA damage, and abnormal mitophagy.
14 Φεβ 2024 · We performed a retrospective chart review of adult patients diagnosed with mitochondrial myopathy at Mayo Clinic (2005–21). We identified 94 patients. Median time from symptom onset to diagnosis was 11 years (interquartile range 4–21 years). Median age at diagnosis was 48 years (32–63 years).
