Αποτελέσματα Αναζήτησης
2 Σεπ 2024 · One of the possible mechanisms of action of citicoline is to modulate autophagy, a cellular process that regulates the degradation and recycling of damaged or unwanted components. Autophagy is essential for maintaining cellular homeostasis and preventing oxidative stress, inflammation, and apoptosis.
20 Οκτ 2016 · Citicoline is an endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.
CDP-choline (also named citicoline) has shown to possess beneficial physiological actions on cellular function. CDP-choline and its hydrolysis products play important roles in phospholipid synthesis and neuronal repair.
15 Σεπ 2024 · This review aims to elucidate citicoline's anti-inflammatory mechanism and its clinical implications in conditions such as ischemic stroke, head trauma, glaucoma, and age-associated memory impairment.
Neuroprotective activity of citicoline has been repeatedly shown in preclinical models of brain ischaemia and trauma, but two recent, large, pivotal clinical trials have revealed no benefits in ischaemic stroke and traumatic brain injury.
27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved ...
16 Φεβ 2023 · It has been proposed to provide neuroprotective effects through diverse mechanisms of action. Taking into account the available literature, citicoline has shown a consistent improvement in cognitive function in patients with MCI, especially of vascular origin.
