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8 Νοε 2023 · A small 2021 study with 100 participants found that citicoline dietary supplements improved overall memory in older adults with age-related memory impairment. A 2023 review also noted that...
20 Οκτ 2016 · Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Neuroprotective activity of citicoline has been repeatedly shown in preclinical models of brain ischaemia and trauma, but two recent, large, pivotal clinical trials have revealed no benefits in ischaemic stroke and traumatic brain injury.
Citicoline is the generic name of a substance identical to cytidine-5’-diphosphocholine (CDP-choline), a natural metabolite presents in minute amounts inside every living cell and playing a crucial role in the synthesis of cellular phospholipids [4]. CDP-choline from an exogenous source, known as citicoline, has been used in medicine since ...
CDP-choline (also named citicoline) has shown to possess beneficial physiological actions on cellular function. CDP-choline and its hydrolysis products play important roles in phospholipid synthesis and neuronal repair.
4 Φεβ 2024 · Researchers have also examined the effects of Citicoline on healthy adult women. The women took 250 mg or 500 mg daily doses of Citicoline for 28 days. It led to significant improvements in cognitive function, including memory (2).
7 Φεβ 2014 · The pharmacological actions of citicoline in the central nervous system seem to be pleiotropic and involve, amongst other things, modulation of some kinases and sirtuin-1. However, our understanding of the mechanisms involved is, at most, fragmentary.