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20 Οκτ 2016 · Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Choline deficiency has been found to be correlated with memory dysfunction. Magnetic resonance spectroscopy studies showed that citicoline intake improves brain uptake of choline in older persons, suggestive of that it shall help in reversing early age-related cognitive changes.
8 Νοε 2023 · A small 2021 study with 100 participants found that citicoline dietary supplements improved overall memory in older adults with age-related memory impairment. A 2023 review also noted that...
However, the subject of citicoline’s mode of action is far from being clarified. The present review is an attempt to classify the major issues concerning the neuroprotective properties of citicoline into three categories: facts , i.e. those that are solved with an acceptable degree of certainty; doubts , i.e. those that are likely ...
22 Απρ 2024 · This comprehensive review seeks to delve into the depths of Citicoline’s mechanisms of action, spanning neurotransmitter synthesis, cellular repair mechanisms, and modulation of neuroplasticity.
Citicoline is a nootropic nucleotide agent with a favorable effect on the augmentation of human memory and cognitive function. Thus, the purpose of this study was to determine the effect of citicoline on human vigilance, visual working memory, and oxidative stress using healthy volunteers.
15 Σεπ 2024 · This review aims to elucidate citicoline's anti-inflammatory mechanism and its clinical implications in conditions such as ischemic stroke, head trauma, glaucoma, and age-associated memory impairment.