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  1. Magnetic resonance spectroscopy studies showed that citicoline intake improves brain uptake of choline in older persons, suggestive of that it shall help in reversing early age-related cognitive changes.

  2. 8 Νοε 2023 · A small 2021 study with 100 participants found that citicoline dietary supplements improved overall memory in older adults with age-related memory impairment. A 2023 review also noted that...

  3. Citicoline is a nootropic nucleotide agent with a favorable effect on the augmentation of human memory and cognitive function. Thus, the purpose of this study was to determine the effect of citicoline on human vigilance, visual working memory, and oxidative stress using healthy volunteers.

  4. Objectives. Subtle deficits in memory in healthy elderly adults are considered to be a normal consequence of aging [i.e., age-associated memory impairment (AAMI)]. The prevalence of cognitive impairment without dementia in the elderly is estimated at 5.4 million, and every year roughly 12% of these individuals go on to develop dementia.

  5. 2 Σεπ 2024 · One of the possible mechanisms of action of citicoline is to modulate autophagy, a cellular process that regulates the degradation and recycling of damaged or unwanted components. Autophagy is essential for maintaining cellular homeostasis and preventing oxidative stress, inflammation, and apoptosis.

  6. Supplementation of citicoline (CDP-choline), a naturally occurring mononucleotide, has shown beneficial effects on memory function and behavior in populations with a wide range of impairments. However, few studies have investigated its effect in healthy older populations. Objective.

  7. 1 Αυγ 2021 · Supplementation of citicoline (CDP-choline), a naturally occurring mononucleotide, has shown beneficial effects on memory function and behavior in populations with a wide range of impairments. However, few studies have investigated its effect in healthy older populations. Objective.

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