Αποτελέσματα Αναζήτησης
7 Απρ 2021 · The prognosis of patients suffering from multifocal glioblastoma is very poor. As was shown before, craniotomy, employing maximum safe resection, is beneficial but already resecting more than 27.7% was associated with prolonged survival in univariate analysis for our cohort.
- A systematic review of multifocal and multicentric glioblastoma
Multiple glioblastoma multiforme (GBM) is classified as...
- Prognostic factors affecting outcome of multifocal or multicentric ...
In view of the advancement of imaging, there is a much...
- Prognosis of patients with multifocal glioblastoma: a case-control ...
Patients with multifocal tumors experienced a significantly...
- A systematic review of multifocal and multicentric glioblastoma
Multiple glioblastoma multiforme (GBM) is classified as multifocal and multicentric GBM according to whether there is communication between the lesions. Multiple GBM is more genetically heterogeneous, aggressive and resistant to chemoradiotherapy than unifocal GBM, and has a worse prognosis.
3 Μαΐ 2023 · In view of the advancement of imaging, there is a much higher incidence of multiple GBM lesions at time of diagnosis than previously reported. Our study shows that mGBM has worse prognosis compared to GBM with singular lesion.
Patients with multifocal tumors experienced a significantly shorter median overall survival of 6 months (95% CI 4-10 months), compared with the 11-month median survival (95% CI 10-19 months) of the matched solitary glioblastoma group (p = 0.02, log-rank test).
11 Μαΐ 2022 · Established prognostic factors are the extent of resection (EOR), performance status (PS) at diagnosis, histological features, patient age, and molecular biomarker status (mutations in isocitrate dehydrogenase 1, IDH1, and promoter methylation of O6-methylguanine DNA methyltransferase, MGMT) [3, 4].
15 Ιουλ 2020 · Glioblastoma multiforme is the most common primary malignant brain tumour in adults with an incidence rate of 3.7 per 100,000 person-years, though geographical variation exists 1. Despite an...
1 Μαρ 2020 · We found that multiple GBMs was a predictor of worse survival (hazard ratio [HR] = 3.57, 95% confidence interval [95%CI]: 1.26–10.13) after adjusting for other significant predictor of radiotherapy (HR = 0.47, 95%CI: 0.23–0.96). Conclusion. Patients with multiple GBMs had worse survival compared to those with single GBM.
