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  1. 7 Απρ 2021 · The prognosis of patients suffering from multifocal glioblastoma is very poor. As was shown before, craniotomy, employing maximum safe resection, is beneficial but already resecting more than 27.7% was associated with prolonged survival in univariate analysis for our cohort.

  2. Patients with multifocal tumors experienced a significantly shorter median overall survival of 6 months (95% CI 4-10 months), compared with the 11-month median survival (95% CI 10-19 months) of the matched solitary glioblastoma group (p = 0.02, log-rank test).

  3. 15 Ιουλ 2020 · Overall estimates of survival among patients with glioblastoma have at least doubled since 2005 to 18% at 2 years and 11% at 3 years. This may reflect treatment response to modern therapeutic ...

  4. Glioblastoma multiforme (GBM) is the most common, aggressive form of brain cancer in adults and is universally fatal. The current standard-of-care options for GBM include surgical resection, radiotherapy, and concomitant and/or adjuvant chemotherapy.

  5. 3 Μαΐ 2023 · In view of the advancement of imaging, there is a much higher incidence of multiple GBM lesions at time of diagnosis than previously reported. Our study shows that mGBM has worse prognosis compared to GBM with singular lesion.

  6. 11 Μαΐ 2022 · Established prognostic factors are the extent of resection (EOR), performance status (PS) at diagnosis, histological features, patient age, and molecular biomarker status (mutations in isocitrate dehydrogenase 1, IDH1, and promoter methylation of O6-methylguanine DNA methyltransferase, MGMT) [3, 4].

  7. Glioblastoma multiforme (GBM) is the most common pri-mary brain tumor encountered in adults. Median survival with optimal treatment is <15 months (1, 2). Although soli-tary lesions are typical for GBM, multiple synchronous gliomatous foci are found at diagnosis with a reported inci-dence of 0.5–20% (3–7).

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