Αποτελέσματα Αναζήτησης
Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. [2] For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea, vomiting, or the kidneys. [3]
12 Φεβ 2024 · The main therapeutic effect of intravenous sodium bicarbonate administration is increasing plasma bicarbonate levels, which buffer excess hydrogen ion (H +) concentration, raising serum pH to combat clinical manifestations of acidosis.
Intravenous sodium bicarbonate (NaHCO3) solution is an appropriate intervention for reversing metabolic acidemia, provided that lung and cardiac function are adequate. NaHCO 3 solution adds HCO 3− to the blood only after the CO 2 load inherent in the NaHCO 3 solution is eliminated by the lungs.
18 Οκτ 2018 · The main strengths of the study include: (1) random assignment of a large number of patients to bicarbonate or no bicarbonate therapy (4-fold more patients than the largest previously published randomized controlled trial), and (2) separate analysis of the impact of bicarbonate therapy on the clinical outcomes of patients who had advanced AKI.
31 Αυγ 2021 · However, treatment with sodium bicarbonate was associated with a reduced need for renal replacement therapy (RRT) in the ICU. Furthermore, in the pre-specified subgroup of patients with acute kidney injury (AKI) (AKIN score 2 or 3), sodium bicarbonate was associated with improved survival and reduced need for RRT [ 5 ].
Sodium Bicarbonate Injection, USP is a sterile, nonpyrogenic, hypertonic solution of sodium bicarbonate (NaHCO 3) in water for injection for administration by the intravenous route as an electrolyte replenisher and systemic alkalizer. Solutions are offered in concentrations of 4.2%, 7.5% and 8.4%.
Intravenous bicarbonate also seems to have a role in preventing acute kidney injury (AKI) after the use of contrast medium, cardiac surgery, or liver transplantation.
