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2,3,7,8-Tetrachlorodibenzo-P-dioxin | C12H4Cl4O2 | CID 15625 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
- Dextran
Dextran is a polysaccharide that differs from others in that...
- Hexachlorophene
Hexachlorophene is an organochlorine compound that is...
- 15th Report on Carcinogens
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to be a...
- Dextran
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a polychlorinated dibenzo-p-dioxin (sometimes shortened, though inaccurately, to simply 'dioxin') [3] with the chemical formula C 12 H 4 Cl 4 O 2. Pure TCDD is a colorless solid with no distinguishable odor at room temperature.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) is formed as an unintentional by-product of incomplete combustion. It may be released to the environment during the combustion of fossil fuels and wood, and during the incineration of municipal and industrial wastes. It causes chloracne in humans, a severe acne-like condition.
21 Δεκ 2021 · 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in humans, both epidemiological and on the mechanism of carcinogenesis.
Dioxin is one of the most toxic and environmentally stable tricyclic aromatic compounds of its structural class. Due to its very low water solubility, most of the 2,3,7,8-TCDD occurring in water is expected to be associated with sediments or suspended material.
This paper provides a critical view of the advances made towards understanding the mechanism of TCDD action. Major topics discussed include the Ah-receptor hypothesis, TCDD as a thyroid hormone agonist, TCDD and vitamin A deficiency, TCDD's effect on receptor regulation, and its effect on intermediary metabolism including related hormonal ...
The congener of most concern is 2,3,7,8-tetrachlorodibenzo-p-dioxin, usually referred to as 2,3,7,8-TCDD or simply TCDD. The oth-er congeners of dioxin are several times less toxic than 2,3,7,8-TCDD. Dioxin concentra-tion in environmental media often is expressed as total TCDD equivalents. Each dioxin con-gener can be multiplied by its ...
