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  1. The lumbar spine is particularly vulnerable to disc herniation due to the high amount of pressure it bears during everyday activities, such as bending, lifting, and sitting. When a herniated disc occurs, it can result in a variety of symptoms depending on the severity and location. Back pain is often the most prominent sign, but leg pain, leg ...

  2. Examples of histological degeneration and edge neovascularity in disc tissues (a–c) and cartilaginous endplate (d).a Edge neovascularity level 1: clefts in the degenerated nucleus pulposus tissue (arrow) with few capillaries and slight monocyte infiltration (H&E, ×100).b Edge neovascularity level 2: the specimen consists of degenerative nucleus pulposus with granulation tissue containing ...

  3. 21 Σεπ 2024 · Lumbar Disc Herniation is a very common cause of low back pain and unilateral leg pain, known as radiculopathy. In rare cases a large disc herniation can lead to Cauda Equina Syndrome which requires emergent diagnosis and treatment.

  4. 16 Ιαν 2023 · A herniated disc is a condition affecting the spine in which the annulus fibrosus is damaged enabling the nucleus pulposus (which is normally located within the center of the disc) to herniate. This can compress the nerves or spinal cord causing pain and spinal cord dysfunction.

  5. 28 Νοε 2023 · Severe Pain and Symptoms: Herniated discs can cause severe and often constant pain, as well as other symptoms such as numbness, tingling, and muscle weakness in the areas served by the affected nerves. The extent of these symptoms can vary depending on the location and size of the herniation.

  6. In the lumbar spine, herniated disc can present with symptoms including sensory and motor abnormalities limited to specific myotome. History in these patients should include chief complaints, the onset of symptoms, where the pain starts and radiates.

  7. In cervical disc herniation (CDH), the indications for surgery consist of six months of persisting symptoms, not responding to conservative treatment. However, high-quality studies are lacking, and a randomized controlled trial is now underway to clarify the indications.

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