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5 Απρ 2018 · Consistently, molecular traits are frequently found to evolve neutrally whereas a large, random set of organismal traits were recently reported to vary largely adaptively. Many more studies of unbiased samples of phenotypic traits are needed to test the general validity of this hypothesis.
7 Μαΐ 2022 · Through statistical and mathematical modeling, neutral theory predicts that the absolute value of s (so |s|) has to be greater than 1/Ne, where Ne is the effective population size, for natural selection to even see and act on the mutation. If |s| is smaller, the mutation is essentially neutral and its fixation rate is dictated by random drift.
The neutral theory explains the fact that different genes and regions of the genome show different levels of polymorphism by assuming that the neutral mutation rate varies among such regions and genes because they are under different functional constraints.
26 Νοε 2018 · The neutral theory of molecular evolution asserts that the majority of genetic variations within a species are neutral; they are neither positive nor negative.
Consistently, molecular traits are frequently found to evolve neutrally whereas a large, random set of organismal traits were recently reported to vary largely adaptively. Many more studies of unbiased samples of phenotypic traits are needed to test the general validity of this hypothesis.
The neutral theory has been revised and broadened in a number of ways since the 1990s, including the emphasis of nearly neutral mutations in the nearly neutral theory, expansion to evolutionary explanations of genomic architectures, and application to phenotypic evolution.
24 Μαρ 2019 · The neutral theory of molecular evolution, proposed in the late 1960s (Kimura 1968; King and Jukes 1969), holds that most genetic variation at the molecular level is evolutionarily neutral, the product of mutation, migration, drift, and mating systems rather than selection.
