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23 Σεπ 2022 · This topic review will provide an overview of the causes, clinical manifestations, diagnosis, and management of neutropenia when it occurs as an isolated or predominant feature.
- Alan G Rosmarin, MD
Overview of neutropenia in children and adolescents. Author...
- Alan G Rosmarin, MD
24 Μαΐ 2021 · Etiological cause can be shown in approximately 75% of neutropenic children. The most common etiological cause is infection. Drug use, nutritional deficiencies, and chronic benign neutropenia are less common causes of neutropenia. The clinical course is largely benign and the mortality rate is very low.
Children with vitamin B 12 or folate deficiency may be neutropenic, but usually have a macrocytic blood picture and hypersegmented neutrophils. Copper deficiency is rare in children with normal gastrointestinal tracts, but would result in a similar clinical picture to vitamin B 12 deficiency.
1 Ιαν 2022 · Tonsillitis, pharyngitis, gingivitis, swollen lymph nodes, and dermatological infections are frequently encountered in toddlers and older children. More than 60% of patients have skin and pharyngeal symptoms, cervical lymphadenopathy, fever, and fatigue more than 5 times a year.
The most common cause of neutropenia in children is infection, found in up to 58% of cases. The focus of infection is most often an URTI, followed by gastroenteritis, LRTI and UTI. Whilst though the most common causative pathogens are viral, neutropenia can be caused by almost any virus, bacteria, or parasite.
Consultant Paediatric Haematologist, Department of Paediatric Haematology and Oncology, Children’s Day Hospital, St James’ University Hospital, Beckett Street, Leeds LS9 7TF, UK; Sally.Kinsey@leedsth.nhs.uk. Abstract. Unravelling the cause of a neutropenia poses a complex diagnostic challenge.
Neutropenia is a rare disorder that causes children to have lower than normal levels of neutrophils, a type of white blood cell that destroys bacteria in the blood and helps protect against infections. Neutropenia can be a very serious condition.
