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  1. 13 Ιαν 2021 · Neutropenia is a serious complication of chemotherapy in patients with solid tumors. The influence of hospital volume on outcomes in patients with neutropenia has been little investigated. We hypothesized that large-volume hospitals would have reduced mortality rates for neutropenic patients compared with small-volume institutions. Methods:

  2. 15 Νοε 2022 · The most common chronic neutropenic disorders (CNDs) are congenital, resulting from genetic variants; cyclic, consisting of recurrent neutropenia with episodes repeating every 3 weeks; and chronic idiopathic neutropenia (CIN), which is characterized by persistent neutropenia of unknown underlying cause and may overlap with autoimmune neutropenia...

  3. 16 Απρ 2019 · Neutropenia is associated with an increased risk of mortality and hospitalisation. Strategies, including the prescribing of colony-stimulating growth factors (CSFs), are adopted when a high risk (> 20%) of neutropenic complications are seen in the clinical trial setting.

  4. 21 Αυγ 2014 · Isolated neutropenia is a common clinical problem seen by primary care physicians and hematologists. The evaluation of neutropenia is dictated by the acuity of the clinical presentation and the duration, age, and clinical status of the patient. In this review, we provide a practical approach to the evaluation of the adult patient with ...

  5. 9 Σεπ 2021 · Likewise, individuals with thrombocytopenia (HR, 1.58; 95% CI, 1.32-1.89; P < .001) and, especially, moderate thrombocytopenia (<100 × 10 9 /L; HR, 4.02; 95% CI, 2.46-6.57; P < .001) were at an increased risk for death. In contrast, neutropenia did not affect OS (HR, 0.88; 95% CI, 0.73-1.06; P = .168), even when lower cutoffs of 1.5 × 10 9 /L ...

  6. 15 Ιουλ 2004 · Results: This preliminary analysis is based on the first 2,222 patients treated to date including 886 (40%) age ≥ 65. One-third did not receive at least four cycles of chemotherapy due to disease progression (55%), refusal (11%), death (11%) and unknown (23%). Neutropenia (ANC <1000) was documented in 40% including SN in 26%.

  7. 29 Νοε 2010 · The average age of included patients was 59.8 years (range, 18-97 years) with 1445 (38.4%) aged 65 and older. Seventy percent (70%) of patients were female with breast cancer representing the most common malignancy (39%) followed by lung cancer (24%), colorectal (14%), lymphoma (15%), and ovary (8%).