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1. www.ahajournals.org › doi › 10Anticoagulants for Acute Ischemic Stroke: Cochrane Review

   www.ahajournals.org › doi › 10

   25 Ιουλ 2022 · Early use of anticoagulants may decrease the volume of infarcted cerebral tissue by reducing the propagation of a thrombus in an intracerebral artery and, therefore, decrease the neurological deficit and risks of disability and death in patients with acute ischemic stroke (AIS).

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2. www.ahajournals.org › doi › 10Advances in Recurrent Stroke Prevention: Focus on Antithrombotic...

   www.ahajournals.org › doi › 10

   14 Απρ 2022 · The past decade has seen significant advances in stroke prevention. These advances include new antithrombotic agents, new options for dyslipidemia treatment, and novel techniques for surgical stroke prevention.

3. www.ahajournals.org › doi › fullPivotal Trials Testing the Efficacy of Novel Anticoagulants for...

   www.ahajournals.org › doi › full

   28 Μαΐ 2024 · Atrial fibrillation (AF) increases the risk of ischemic stroke, accounts for about one quarter of all ischemic strokes worldwide, and is associated with a substantial morbidity and mortality. 1 Oral anticoagulation can reduce the stroke risk in nonvalvular AF by two thirds by using vitamin K antagonists or non‐vitamin K‐dependent oral anticoagul...

4. newsroom.heart.org › news › newer-generation-clot-busting-stroke-medication-cutsNewer generation, clot-busting stroke medication cuts the risk of...

   newsroom.heart.org › news › newer-generation-clot-busting-stroke-medication-cuts

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   3 Φεβ 2022 · Tenecteplase is a newer generation medication administered by a single injection into a blocked blood vessel. Both medications are approved for use in dissolving clots in blocked heart arteries, and tenecteplase is sometimes used off-label to treat ischemic strokes.

5. www.sciencedirect.com › science › articleNew anticoagulants: Moving beyond the direct oral anticoagulants

   www.sciencedirect.com › science › article

   1 Ιαν 2021 · Anticoagulants are a mainstay for the prevention and treatment of thrombosis, which creates a global need for effective and safe agents. However, recent advances have addressed many of the unmet needs. Thus, DOACs have replaced VKAs for stroke prevention in most patients with AF and for VTE treatment.

6. pmc.ncbi.nlm.nih.gov › articles › PMC4550032New oral anticoagulants – a practical guide - PMC - PubMed...

   pmc.ncbi.nlm.nih.gov › articles › PMC4550032

   Oral direct inhibitors of thrombin and activated factor Xa are approved as new anticoagulant drugs. In contrast to vitamin K antagonists (VKA) and heparins, the new agents have single targets in the coagulation cascade and more predictable ...

7. www.sciencedirect.com › science › articleCurrent and potentially novel antithrombotic treatment in acute...

   www.sciencedirect.com › science › article

   15 Φεβ 2024 · Current anticoagulant therapies are associated with up to 2 % of hemorrhagic strokes. •. New antithrombotic therapies are needed for primary and secondary prevention of AIS. Abstract. Acute ischemic stroke (AIS) is the most common type of stroke and requires immediate reperfusion.