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  1. Increased levels of interferon (IFN)-γ and interleukin (IL)-6 have been found in metal-allergic patients with joint arthroplasties. 8, 9 Analysis of tissues adjacent to implanted metals in patients with metal hypersensitivity have demonstrated elevated levels of immune cells/markers, including CD3þ T lymphocytes, CD4þ cells, CD11cþ ...

  2. Our patient was known to have a true nickel allergy confirmed by previous allergy testing. We obtained industry samples of each type of valve (Edwards Sapien 3 and Medtronic Evolut CoreValve) and applied the stent frames to the patient's skin to evaluate for allergic response.

  3. 15 Οκτ 2021 · We here review the immune events involved in the mediation of metal allergies. We focus on nickel (Ni), cobalt (Co) and palladium (Pd), because these allergens are among the most prevalent sensitizers (Ni, Co) and immediate neighbors in the periodic table of the chemical elements.

  4. Allergic nickel dermatitis can be treated with topical corticosteroids or calcineurin inhibitors. Hand eczema in nickel-allergic individuals can be treatment-resistant, in particular in cases with a mixed aetiology with irritant or atopic components.

  5. 25 Νοε 2021 · The conclusions reached are that (a) sensitization can potentially be acquired as the result of exposure to implants containing nickel, but is not a common occurrence; (b) sensitization to...

  6. 22 Ιουλ 2023 · Nickel allergy is a type of contact dermatitis caused by direct contact with nickel. It is the most common identifiable cause of metal-related contact dermatitis and may be encountered in a variety of healthcare settings, from primary care clinics to emergency departments.

  7. 27 Μαρ 2012 · Twenty-nine allergic patients who underwent coronary stent implantation were compared with a nonallergic group (n=250) matched for demographics and a propensity score for allergy to metal. Hypersensitivity to nickel was reported in 26 of 29 and chromium in 9 of 29. Patch testing performed in 11 of 29 patients was positive in all.

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