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  1. 1 Ιουλ 2015 · Understanding the molecular mechanisms underlying nicotine addiction enables the development of effective strategies for smoking cessation. Nicotine depletion repletion cycle.

  2. 26 Οκτ 2016 · Background: Nicotine is an addictive substance present in cigarette smoke that causes a great number of health effects and is a leading cause of preventable death. Figure 1 illustrates the...

  3. 31 Μαρ 2020 · Nicotine addiction involved not only counter adaptive changes of endogenous serotonin and its receptor system, but also adaptive changes of many other neuronal transmitter systems.

  4. Nicotine addiction and dependence is a chronic relapsing disease driven by addiction to nicotine. Proactive treat-ment for all tobacco users, regardless of their readiness to quit, is recommended. First-line tobacco cessation medi-cations include nicotine replacement therapy, bupropion, and varenicline.

  5. Key Clinical Points. Tobacco Addiction. Tobacco addiction is a chronic relapsing disorder that accounts for more than 480,000 deaths annually in the United States and is characterized by...

  6. Treatment is targeted towards dealing with physical addiction to nicotine, psychological reliance on the effects of nicotine, and behavioral aspects of tobacco use. Several pharmacological and nonpharmacological interventions are effective in treating nicotine dependence and evidence-based guidelines have been developed.

  7. Is nicotine addictive? Yes. Most smokers use tobacco regularly because they are addicted to nicotine. Addiction is characterized by compulsive drug-seeking and use, even in the face of negative health consequences. The majority of smokers would like to stop smoking, and each year about half try to quit permanently.

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