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  1. Parathyroidectomy is the definitive cure for primary hyperparathyroidism, and no medical therapies have been approved by the Food and Drug Administration for this disorder.

  2. The purpose of this chapter is to discuss the options available for patients with primary hyperparathyrodism (PHPT) not undergoing parathyroidectomy (PTx). Adequate hydration should be recommended in all patients.

  3. 30 Αυγ 2024 · Among such patients, the majority are women over age 50 years who are asymptomatic. This topic reviews the management of PHPT in general and the risks and benefits of medical versus surgical management in asymptomatic patients.

  4. Parathyroidectomy is the definitive cure for primary hyperparathyroidism, and no medi-cal therapies have been approved by the Food and Drug Adminis-tration for this disorder.

  5. 19 Αυγ 2022 · For Task Force 4 on the Management of PHPT, Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology addressed surgical management of asymptomatic PHPT and nonsurgical medical management of PHPT.

  6. Non-surgical management of primary hyperparathyroidism Monitoring includes at least annual measurements of calcium, 25(OH)D and creatinine with estimated eGFR (or preferably creatinine clearance measurement).

  7. Parathyroidectomy, the only definitive cure for PHPT, is indicated in symptomatic and asymptomatic older PHPT patients with skeletal and renal disease. It is as effective in older patients as it is in younger patients.

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