Αποτελέσματα Αναζήτησης
22 Οκτ 2020 · Normal mode analysis is a technique, based on the physics of small oscillations, that can be used to describe the flexible states accessible to a protein around an equilibrium position. The idea is that when an oscillating system at equilibrium, for example a protein in an energy minimum conformation, is slightly perturbed, a restoring force ...
4 Απρ 2024 · Abstract. We propose a new way of utilizing normal modes to study protein conformational transitions. Instead of considering individual modes independently, we show that a weighted mixture of low-frequency vibrational modes can reveal dynamic information about the conformational mechanism in more detail than any single mode can.
29 Νοε 2019 · Normal mode analysis provides a powerful tool in biophysical computations. Particularly, we shed light on its application to protein properties because they directly lead to biological functions.
10 Σεπ 2019 · Normal mode analysis (NMA) is a technique that can be used to describe the flexible states accessible to a protein about an equilibrium position. These states have been shown repeatedly to have functional significance.
30 Μαρ 2009 · Normal mode analysis (NMA) is better suited to study the slow dynamics of proteins. We briefly describe the theory underlying NMA and the simplifications used to render it tractable for (large) proteins.
22 Οκτ 2020 · This web-based server uses improved normal mode analysis (NMA) for the characterization of various dynamic properties of biomolecules, like protein flexibility and stability, by means of an...
Here, we analyze the capacity of NMA in internal coordinate space to predict protein motion, its intrinsic flexibility, and atomic displacements, using protein models instead of native structures, and the possibility to use it for model refinement.
