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1. emedicine.medscape.com › article › 2090462-overviewValproic Acid Level: Reference Range, Interpretation ... -...

   emedicine.medscape.com › article › 2090462-overview

   • Αποθηκευμένο αντίγραφο

   20 Νοε 2019 · A valproic acid level measures the amount of valproic acid in the blood: either the total level or free level of the drug. Monitoring of serial valproic acid levels is required to...

   • Seizure Disorders in Pregnancy

     Valproic acid. A syndrome of specific craniofacial...

   • Myoclonic Epilepsy

     Juvenile myoclonic epilepsy (JME) is an idiopathic...

   • Bipolar Disorder

     Bipolar disorder, bipolar disorder is a common, severe, and...

   • Absence Seizures

     Absence seizures are a type of generalized non-motor...

2. www.ncbi.nlm.nih.gov › books › NBK559112Valproic Acid - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK559112

   19 Μαρ 2024 · Therapeutic ranges of valproic acid: The therapeutic range for total valproate in epilepsy is 50 to 100 mcg/mL, and in mania, it is 50 to 125 mcg/mL. VPA generally takes around 14 days to achieve maximum concentration within the body.

3. www.ncbi.nlm.nih.gov › books › NBK482298Antiepileptic Drug Monitoring - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK482298

   1 Μαΐ 2024 · Patient-Specific Antiepileptic Drug Levels. A single antiepileptic drug level can reasonably be assessed while the patient is seizure-free, serving as a benchmark for future reference if seizure control deteriorates or symptoms suggestive of toxicity develop. Regular monitoring of valproic acid levels is crucial in cases of toxicity, with ...

4. cdn.mdedge.com › files › s3fs-publicIs your patient’s valproic acid dosage too low or high? Adjust it...

   cdn.mdedge.com › files › s3fs-public

   Valproic. acid (VPA) often is used to treat mania in bipolar disorder, and it has a therapeutic range of 50 to 125 μg/mL of total serum concentration.1 VPA binds highly to albumin, resulting in free drug concentrations (5 to 15 mg/L) Table 1.

5. pmc.ncbi.nlm.nih.gov › articles › PMC4100435Time Matters!: When is the Right Time to Estimate Serum Valproic...

   pmc.ncbi.nlm.nih.gov › articles › PMC4100435

   Chart depicting the individual subject's serum valproic acid levels at 12 and 24 h. It is observed that measuring serum VPA levels at 24 h is recommended and provides a more accurate value for patients on OD dosage.

6. meridian.allenpress.com › Dosing-of-valproate-in-an-elderly-population-withDosing of valproate in an elderly population with dementia:...

   meridian.allenpress.com › Dosing-of-valproate-in-an-elderly-population-with

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   1 Μαΐ 2012 · The mean age of all patients included (n=62) was 78 + 8.1 years. Males accounted for 53% of the population and Caucasians made up 70% of the cohort. Patients had a mean weight, starting dose, and initial mg/kg dose of 71 + 12.6 kg, 409 mg + 150.4 mg, and 5.96 mg/kg + 2.1 mg/kg, respectively.

7. accesspharmacy.mhmedical.com › contentChapter 12. Valproic Acid - McGraw Hill Medical

   accesspharmacy.mhmedical.com › content

   The generally accepted therapeutic range for total valproic acid steady-state concentrations is 50–100 μg/mL, although some clinicians suggest drug concentrations as high as 175 μg/mL with appropriate monitoring of serum concentrations and possible adverse effects.