Αποτελέσματα Αναζήτησης
Scenarios with increased transcription (black arrows), decreased transcription (red X marks) or unaltered transcription (dashed arrows) are shown. Here, we review how the non-random organization of DNA relative to the nuclear periphery affects genome expression and stability.
10 Μαρ 2022 · During semi-conservative replication, DNA polymerases copy the parental strands using RNA as a primer. DNA synthesis is continued by the addition of dNTPs to the 3′ end of the growing strands, ensuring the reliable replication of both DNA strands.
By templating DNA synthesis from its own RNA subunit, telomerase counteracts telomere shortening, which can accumulate over DNA replication and cell division cycles and induce senescence.
The nuclear stability curve depicts the binding energy per nucleon as a function of the mass number (A) of atomic nuclei. The curve shows that nuclei with intermediate mass numbers, around A = 56 for iron, have the highest binding energy per nucleon, indicating the greatest stability.
15 Απρ 2021 · The nuclear envelope (NE) not only shields the genetic material inside the nucleus, maintains the dynamic shapes of nucleus, and regulates nuclear exchange with cytosol, but also participates in DNA replication, damage repair and transcription regulation.
As found in our study, by influencing the average density of negatively charged DNA, the nucleus size determines the mean electrostatic potential of the cell nucleus with respect to the cytoplasm, which has a profound effect on the stability of nucleosomes (Figs. 4, S2, and S3).
12 Φεβ 2018 · The nucleolus is the major site for synthesis of ribosomes, complex molecular machines that are responsible for protein synthesis. A wealth of research over the past 20 years has clearly...
