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  1. ONCEPT ® Canine Melanoma Vaccine, DNA aids in extending survival times of dogs with stage II or stage III oral melanoma and for which local disease control has been achieved (negative local lymph nodes or positive lymph nodes that were surgically removed or irradiated). 1

  2. 15 Σεπ 2022 · The canine melanoma vaccine is effective at improving survival times, has minimal side effects, and can be used with surgery and/or radiation. Every case is unique, but most dogs diagnosed with oral melanoma can benefit from this therapeutic vaccine as a part of their treatment plan.

  3. The average cost per injection is $$$ to $$$$ (see Cost Key), making the overall cost comparable with that for chemotherapy. Dogs receive an initial induction series of 4 injections 2 weeks apart and then a booster q6mo. Currently, the vaccine is only available to veterinary oncologists (or internists in regions without oncologists).

  4. The Oncept melanoma vaccine is xenogeneic DNA vaccine targeting tyrosinase. It is USDA approved for treatment of stage II to III canine oral melanoma and is also used off-label for melanomas arising in other locations and in other species.

  5. Systemic immunotherapy for adjuvant treatment of canine melanoma may be more promising than chemotherapy. A xenogeneic DNA vaccine, Oncept (Boehringer Ingelheim, petcancervaccine.com ), has made headway as the first conditionally approved immunotherapy for the treatment of canine OMM.

  6. The goal of the Oncept vaccine is to stimulate the immune system to target melanoma cells in the body. Side effects of the melanoma vaccine are minimal to none; a small subset of dogs may experience mild redness or bruising at the injection site, but systemic effects are generally not observed. While a small subset of dogs may experience a ...

  7. 28 Οκτ 2022 · The Oncept melanoma vaccine is xenogeneic DNA vaccine targeting tyrosinase. It is USDA approved for treatment of stage II to III canine oral melanoma and is also used off-label for melanomas arising in other locations and in other species.

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