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ONCEPT ® Canine Melanoma Vaccine, DNA aids in extending survival times of dogs with stage II or stage III oral melanoma and for which local disease control has been achieved (negative local lymph nodes or positive lymph nodes that were surgically removed or irradiated). 1. Clinical Benefits. Canine Melanoma Vaccine, DNA is a safe, effective ...
15 Σεπ 2022 · FAQ #5: What is the ONCEPT® melanoma vaccine for dogs? Prior to 2007, surgery, chemotherapy, and radiation were the only options for treating canine oral malignant melanoma. With the development of a melanoma vaccine called ONCEPT, the veterinary community gained an exciting treatment option.
The average cost per injection is $$$ to $$$$ (see Cost Key), making the overall cost comparable with that for chemotherapy. Dogs receive an initial induction series of 4 injections 2 weeks apart and then a booster q6mo. Currently, the vaccine is only available to veterinary oncologists (or internists in regions without oncologists).
The Oncept melanoma vaccine is xenogeneic DNA vaccine targeting tyrosinase. It is USDA approved for treatment of stage II to III canine oral melanoma and is also used off-label for melanomas arising in other locations and in other species.
Systemic immunotherapy for adjuvant treatment of canine melanoma may be more promising than chemotherapy. A xenogeneic DNA vaccine, Oncept (Boehringer Ingelheim, petcancervaccine.com ), has made headway as the first conditionally approved immunotherapy for the treatment of canine OMM.
Immunotherapy (Oncept®) Post-operatively for localized disease or disseminated disease: One vaccine every 2 weeks for a total of 4 vaccines. Boosters given every 6 months: $600 per visit
Recent advances in treatment for the metastatic potential of melanoma have occurred with the generation the melanoma vaccine, Oncept. Oncept has now become part of the standard adjuvant treatment in dogs with high risk melanoma Side effects of the melanoma vaccine are minimal to none; a small subset of dogs may experience mild
