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Download scientific diagram | Expression of E-cadherin, CK, a-SMA, vimentin in HK-2 cells by immunochemistry. (A-C)The HK-2 cells under 30 mM glucose(B) or 30 mM glucose+cont siRNA(C)...
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Download scientific diagram | Expression of E-cadherin, CK,...
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Here, we showed that treatment of cobalt chloride (CoCl2), a hypoxia mimic, in HK-2 tubular epithelial cells induced PHD2 and HIF-1/2α expression as well as cell apoptosis and autophagy...
HK-2 cells exhibit a well-differentiated phenotype characteristic of proximal tubule cells (PTCs) found in the human kidney. This unique trait makes HK-2 cells a valuable in vitro model for studying renal physiology, cell processes, and responses to various stimuli.
Similarly, renal epithelial cells (HK-2 cells) showed robust expression of netrin-1 in conjunction with netrin-1 induction following exposure to ambient hypoxia (1% oxygen over 0-24 h,...
26 Σεπ 2023 · We investigated gene and protein expression of HK-2 cells cultured in six medium formulations. TGF-β1 increased the expression of ACTA2, TGFB1, COL4A1, EGR2, VIM and CTGF genes while reducing PPARG in all medium formulations.
12 Οκτ 2023 · When human kidney tubular cells (HK-2) were stimulated with TGF-β1, they produced and released increased amounts of exosomes (TGFβ-Exo), which prevented renal interstitial fibroblasts from...
2 Οκτ 2020 · In this study, the architecture and morphology of HK-2 cells were observed dynamically by multiple imaging methods. AFM (atomic force microscopy)-based single-cell force spectroscopy was employed to investigate the dynamic mechanics quantitatively.