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24 Ιουν 2023 · Asthma is most likely transmitted by multiple genes, with some variation of locus heterogeneity and polygenic inheritance leading to asthma expression being multifaceted. Atopy or IgE antibodies attack specific antigens or pollutants, which can contribute to the disease.
As we learn more about the pathophysiology, phenotypes, and genetics of asthma, treatments will become available to ensure adequate asthma control for all persons and, ideally, to reverse and even prevent the asthma processes.
5 Σεπ 2022 · This review is focused on the pathogenesis and biomarkers of asthma induced by allergens, infection, and pollutants. 1. Pathological Mechanisms of Asthma. Although asthma is classified into Th2-high and Th2-low asthma, the disease can be induced by mixed airway inflammation.
During an asthma episode, inflamed airways react to environmental triggers such as smoke, dust, or pollen. The airways narrow and produce excess mucus, making it difficult to breathe. In essence, asthma is the result of an immune response in the bronchial airways. [3]
21 Ιουλ 2020 · Asthma is a chronic disorder of the airways characterized by variable and recurring airway inflammation, bronchial hyperresponsiveness, bronchoconstriction, vasodilatation, airway edema, and activation of sensory nerve endings.
19 Ιαν 2023 · Patients with severe asthma often have co-existing conditions contributing to their symptoms, mandating a multidimensional management approach. In this Seminar, we provide a clinically focused overview of asthma; epidemiology, pathophysiology, diagnosis, and management in children and adults.
We can understand more about the pathophysiology of asthma by looking at the airways of the lungs. Healthy lungs have relaxed smooth muscles, they are not inflamed and there is no excess mucus. In the lungs of a person presenting with asthma, there is smooth muscle tightening or constriction, inflammation inside the airway, and increased mucus.
