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  1. 21 Ιουν 2022 · Glycemic control in T2DM patients can be evaluated using three parameters: glycosylated hemoglobin (HbA1c), fasting blood glucose (FBG), and postprandial glucose (P PG). Among these, glycosylated hemoglobin is the gold standard for the estimation of glycemic control [ 7 ].

  2. 21 Δεκ 2022 · Impaired proinsulin-to-insulin processing in pancreatic β-cells is a key defective step in both type 1 diabetes and type 2 diabetes (T2D) (refs. 1,2), but the mechanisms involved remain to be ...

  3. 15 Νοε 2021 · The general target for glucose control in type 2 diabetes should be less than 7% (53 mmol/mol); an HbA 1c target between 7·5% and 8% (58–64 mmol/mol) could be more appropriate in patients using multiple drugs, with cognitive impairment, short life expectancy, chronic kidney disease or severe cardiovascular disease.

  4. The primary objective of this study is to analyze the most up-to-date evidence regarding whether and how blood sugar regulation impacts cardiovascular health promotion and disease prevention by carrying out an umbrella review. ... Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med 2008;358:2560 ...

  5. Although there is evidence indicating transcriptional and functional heterogeneity in human beta cells, it is unclear whether this heterogeneity extends to the expression level of the enzymes that process proinsulin to insulin in beta cells. To ...

  6. 17 Μαρ 2017 · Key Points. Fluctuations in blood levels of glucose in diabetes mellitus manifest on several clinically relevant timescales, from gradual months-long changes in average glycaemia (reflected by...

  7. 19 Ιαν 2024 · In this systematic review and meta-analysis we have identified a new nonlinear dose-response relationship between physical activity and glucose control in people with type 2 diabetes. The optimal physical activity dose to achieve the greatest reductions in HbA 1c regardless of baseline HbA 1c level was 1,100 MET min/week.

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