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26 Ιουν 2023 · Summarize some of the various presenting signs and symptoms that would accompany clonidine toxicity. Review treatment and management strategies available for clonidine toxicity.
16 Ιουλ 2024 · Clinical effects are not entirely dose related. As little as 20 micrograms/kg can cause significant CNS depression in some while higher doses are tolerated well in others. Onset of symptoms is usually within 2 hours and definitely by 6. The onset of toxicity can be rapid; Children: 2 tablets is potentially lethal
13 Μαρ 2024 · Clonidine exposure is frequently symptomatic in children, and pediatric clonidine poisoning is frequently complicated by coma and respiratory depression; fortunately, deaths due to pediatric exploratory ingestion of clonidine are rare [2-6].
1 Ιαν 2021 · Clinical findings of pediatric clonidine exposure include mental status depression, bradycardia, hypotension, miosis, respiratory depression, and hypothermia (2, 13, 14). This pattern of findings closely mirrors the opioid toxidrome, making ascertainment of the correct diagnosis challenging.
14 Φεβ 2021 · In this retrospective single-center review, pediatric patients tolerated CAS poisoning well. CAS poisoning did not directly result in death. Most pediatric patients with CAS poisoning...
26 Ιουν 2023 · Overdose results in a toxidrome not easily identified. Even at therapeutic doses, clonidine has a number of anticholinergic side effects that include dry mouth, constipation, and sedation. However, at toxic doses, it can cause hemodynamic instability and depression.
14 Φεβ 2021 · In this retrospective single-center review, pediatric patients tolerated CAS poisoning well. CAS poisoning did not directly result in death. Most pediatric patients with CAS poisoning had short hospital lengths of stay and did not undergo critical care interventions.