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  1. 19 Νοε 2020 · Complications following therapeutic circumcision are most likely due to either the more complicated surgical procedure in pathological tissue requiring more manipulation, due to altered presence of pathogenic bacteria, or due to ongoing penile pathology existing prior to circumcision.

  2. 11 Ιουλ 2024 · Surgical margins of >1 mm are now accepted, with the risk of local recurrence being low. According to a recent systematic review, local recurrence and positive surgical margin rates after glansectomy are 2.6%-16.7% and 2.9%-22.6%, respectively.

  3. 2 Σεπ 2024 · However, the treatment of penile cancer requires large radiation doses, which results in a relatively high rate of complications such as urethral strictures, secondary infections, urethral mucositis, localized edema, pain, urethrocutaneous fistulas, meatal stenosis, and superficial tissue necrosis.

  4. Penile cancer is rare in circumcised men, particularly if they are circumcised as newborns. Penile cancer in men and cervical cancer in women have a strong correlation with human papilloma virus (HPV) infection [1, 2].

  5. 1 Οκτ 2024 · Local recurrences involved 33 (50.3%) patients and required either organ-sparing surgery (laser ablation, glansectomy or partial penectomy) or total penectomy. Compared to low-grade tumors (G1), high-grade PeCa (G3) emerged to be characterized by a higher risk of local recurrences (HR 6.1, 0.97–38.5, p = 0.05).

  6. 16 Ιαν 2021 · Several studies have demonstrated that neonatal circumcision reduces the incidence of penile cancer by promoting better hygiene and decreasing chronic inflammatory conditions like balanoposthitis and lichen sclerosus et atrophicus, two key risk factors for penile cancer [28–32].

  7. 22 Μαρ 2016 · Organ-preserving approaches to surgical treatment of the primary tumour, rather than total penectomy, exemplify a major paradigm shift in the clinical management of penile cancer.

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