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  1. 1 Οκτ 2024 · Radical circumcision is a safe management option for patients with superficial tumors (Tis, Ta and T1), as penile lesions limited to the foreskin comprise 15.2% of cases. It eradicates the inflammatory environment which may foster the disease progression.

  2. 11 Ιουλ 2024 · Penile cancer is a rare genital malignancy with an estimated global incidence of 36 068 new cases in 2020. 1 In Western Europe and the United States, the age-adjusted incidence of penile cancer is 0.3-2.1 per 100 000. 2 Conversely, in countries where circumcision is routine practice due to religious or cultural reasons, 3 penile cancer is ...

  3. 16 Ιαν 2021 · In patients with penile cancer and palapable or radiologically evident inguinal lymph node metastases, the InPACT (NCT02305654) Phase III trial, is an important trial which aims to determine the relative benefits and sequencing of surgery, chemotherapy and chemoradiotherapy.

  4. 2 Σεπ 2024 · Wide local surgical excision of the primary tumor (eg, circumcision where appropriate) remains the gold standard for rapid definitive treatment of penile cancer. [2] [117] Split-thickness or full-thickness skin grafts may be needed to accomplish this.

  5. Organ-sparing surgery, such as radical circumcision and wide local excision is an appropriate treatment option for selected penile cancer patients. It preserves sexual and urination function without significantly increasing the risk of recurrence.

  6. 5 Σεπ 2023 · The principles of surgical management of penile cancer are [1] oncologic control, by safe excision of the primary tumour with an adequate margin, and [2] preservation of sexual function, urinary function, and quality of life (QOL) using reconstructive techniques.

  7. 1 Οκτ 2022 · Being diagnosed with PeCa and undergoing treatment may result in significant physical and psychosexual side effects. The GLOBOCAN 2020 database, compiled by the International Agency for Research on Cancer estimated the global cancer incidence and mortality for 36 cancers in 185 countries.

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