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  1. 16 Σεπ 2021 · In this article, we present three case scenarios devised to illustrate the key principles of safe prescribing antiepileptic drugs, immunosuppression and anticoagulants in pregnancy and their potential teratogenic effects. In addition, we discuss the management of pregnancy complicated with potential teratogenicity.

  2. 26 Ιουν 2020 · This review collates examples of drugs with known recommendations for dose adjustment during pregnancy, in addition to providing an example of the potential use of PBPK models in dose adjustment recommendation during pregnancy within the context of drug-drug interactions.

  3. 26 Ιουλ 2022 · However, the available national guidance, online evidence-based databases, relevant academic resources and professional advice available from specialised centres can all help healthcare professionals with decision-making on treatment options for pregnant women.

  4. 18 Δεκ 2020 · In limited clinical settings, the appropriate doses during pregnancy are sometimes determined by obtaining blood levels of the drug (eg, antiseizure medications) or by pharmacodynamic observations (eg, antihypertensive drugs).

  5. 26 Αυγ 2024 · Only four reference guides provided risk categories for drug use during pregnancy. Based on whether the evidence was sufficient, Micromedex categorized the drugs into 5 levels: contraindicated, fetal harm has been demonstrated, may cause fetal harm, fetal risk cannot be ruled out, and fetal risk is minimal.

  6. 25 Μαρ 2022 · Several oral dosage forms intended for paediatric oral administration exist and include both solid (tablet, capsules, orodispersible formulations, powder for reconstitution and chewable tablets) and liquid (solutions, suspensions, elixirs and syrups) dosage forms.

  7. 12 Ιουλ 2022 · There was also heterogeneity in the recommended aspirin dose in pregnancy: 25 % of the CPGs included in the present review reported a daily dosage of 50–150 mg, 18.7 % (3/16) 100–150 mg, 12.5 % (2/16) 81 mg, while one CPG 75 mg and 60 mg, respectively.

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