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2.3.6. The required dose from a Phosphate Polyfusor® is usually given over 12 – 24 hours but can be given over 6 – 12 hours if necessary, according to severity. 2.3.7. It is common to use only a proportion of the Polyfusor® bottle. To avoid overdosing the patient, ensure the infusion is stopped when the prescribed volume has been infused.
Doses for intravenous phosphate vary in the literature and suggested regimens have included weight based dosing regimens of 0.2-0.5mmol/kg/day up to a maximum of 50mmol. WAHT-PHA-011
The appropriate volume (see table above) should be administered over 24 hours, but can be given more quickly (over a minimum of 6 hours) if required, providing this can be safely tolerated by the patient. Repeated doses may be required on subsequent days after checking of serum phosphate levels.
Phosphate Dosing calculator for hospitalized patients. Treatment of hypophosphatemia including available oral agents and IV dosing
6 Μαρ 2024 · Hypophosphatemia can be induced by decreased net intestinal absorption, increased urinary phosphate excretion, or acute movement of extracellular phosphate into cells. This topic will review the evaluation and treatment of patients with hypophosphatemia.
Suggested starting doses: Mild Hypophosphataemia (0.6-0.79mmol/L) No treatment required. Moderate Hypophosphataemia (0.3-0.59mmol/L): Phosphate Sandoz® 1-2 tablets orally three times daily (each tablet contains 16mmol phosphate, 3mmol potassium and 20mmol sodium).
Phosphate-Sandoz ® • Usually 1-2 tablets, three times daily. Tailor dose according to individual need. Inform patient that diarrhoea is a common side effect. Advise to take plenty of water. May need dose reduction. • If end stage kidney disease, renal transplant or eGFR <45 mL/min/1.73m2 discuss with nephrology
