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  1. Brain: Alcohol interferes with the brain’s communication pathways, and can affect the way the brain looks and works. These disruptions can change mood and behavior, and make it harder to think clearly and move with coordination .

    • Alcohol Topics a to Z

      Alcohol's Effects on Health ... National Institute on...

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      A person must wait for the body to finish clearing the toxic...

    • About Niaaa

      Alcohol's Effects on Health. Alcohol's Effects on Health;...

    • Research

      The NIAAA is the lead agency for U.S. research on the...

    • PMC Free Article

      Investigators use a variety of methods to study...

  2. Alcohol’s Effects on the Liver, the Neuroendocrine System, and Bone. The medical consequences of chronic alcohol abuse and dependence have been well documented in adults. They include liver disease, lung disease, compromised immune function, endocrine disorders, and brain changes.

  3. Well-supported scientific evidence shows that disruptions in three areas of the brain are particularly important in the onset, development, and maintenance of substance use disorders: the basal ganglia, the extended amygdala, and the prefrontal cortex.

  4. Investigators use a variety of methods to study alcoholism-related brain damage, including examining brains of deceased patients as well as neuroimaging, a technique that enables researchers to test and observe the living brain and to evaluate structural damage in the brain.

  5. 1 Δεκ 2021 · We discuss seven distinct but tightly interlinked levels of effects of alcohol on the brain, starting from genetic factors that confer susceptibility to AUD (level 1), through alcohol-induced changes in epigenetic mechanisms (level 2), transcriptional activity (level 3), alternative splicing (level 4), translation (level 5), and post ...

  6. Although environmental and genetic factors contribute to the etiology of alcohol use disorders, it is ethanol’s actions in the brain that explain (1) acute ethanol-related behavioral changes, such as stimulant followed by depressant effects, and (2) chronic changes in behavior, including escalated use, tolerance, compulsive seeking, and dependence.

  7. Alcohol interferes with the brains communication pathways and can affect the way the brain looks and works. Alcohol makes it harder for the brain areas controlling balance, memory, speech, and judgment to do their jobs, resulting in a higher likelihood of injuries and other negative outcomes.

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