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  1. Alcohol’s Effects on the Liver, the Neuroendocrine System, and Bone. The medical consequences of chronic alcohol abuse and dependence have been well documented in adults. They include liver disease, lung disease, compromised immune function, endocrine disorders, and brain changes.

  2. 25 Μαρ 2022 · Alcohol consumption represents a major factor of morbidity and mortality, with a wide range of adverse medical implications that practically affect every organ system. It is the fifth major cause of deaths in men and women and causes up to 139 million disability-adjusted life years.

  3. 18 Μαΐ 2022 · If your pattern of drinking results in repeated significant distress and problems functioning in your daily life, you likely have alcohol use disorder. It can range from mild to severe. However, even a mild disorder can escalate and lead to serious problems, so early treatment is important.

  4. 1 Ιουλ 2014 · Alcohol’s effects on neurological function and disease are carried out through the actions of a variety of brain neurotransmitters, where there is a complex interplay between excitatory and inhibitory systems. Alcohol, consistent with a variety of other drugs of abuse, increases dopamine levels.

  5. 1 Σεπ 2016 · Common pathophysiological mechanisms of alcohol-induced tissue and organ injury are inflammation, increased oxidative stress, abnormal posttranslational modifications of proteins, impaired anabolic signaling, upregulation of catabolic processes, and dysregulation in lipid metabolism and signal transduction pathways ( 51, 55 ).

  6. 16 Μαρ 2024 · Alcohol, the most commonly used substance in the United States, has far-reaching health consequences that impact not only individual patients but the entire healthcare system. Alcohol use in and of itself is not problematic but exists along a spectrum from low-risk use to alcohol use disorder (AUD).

  7. Drinking too much – on a single occasion or over time – can take a serious toll on your health. Here’s how alcohol can affect your body: Brain: Alcohol interferes with the brain’s communication pathways, and can affect the way the brain looks and works.

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