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  1. Discussion. Alcohol consumption is well known to have dose–response relationships for regulating blood pressure and glucose metabolism, contributing to the risks of developing hypertension, diabetes and hypertriglyceridemia, and may lead to cardiomyopathy, atrial fibrillation, stroke, etc. [13–20, 24].Individuals with excessive consumption of alcohol cannot control their alcohol use, and ...

  2. 10 Αυγ 2015 · Relative to combined abstainers, reductions in the risk of type 2 diabetes were present at all levels of alcohol intake <63 g/day, with risks increasing above this threshold. Peak risk reduction was present between 10–14 g/day at an 18% decrease in hazards.

  3. 17 Απρ 2012 · Chronic use of alcohol is considered to be a potential risk factor for the incidence of type 2 diabetes mellitus (T2DM), which causes insulin resistance and pancreatic β-cell dysfunction that is a prerequisite for the development of diabetes.

  4. In patients with asthma or COPD, AUD is associated with increased disease related morbidity, increased healthcare utilization and increased healthcare costs. This impact persists after adjusting for the increased rates of tobacco use, substance misuse and chronic disease seen within this cohort.

  5. 5 ημέρες πριν · The interaction of variant rs56221195 with alcohol intake exhibited a pronounced effect on the liver insulin resistance index (LIRI) in the discovery set, corroborated in the validation set (combined p=1.32 × 10−11). Alcohol consumption did not significantly affect LIRI in rs56221195 wild-type (TT) carriers, but a strong negative association ...

  6. The ADS also was the basis for the ICD10 alcohol dependence criteria. In the ICD10, the “secondary” alcohol category is called harmful use (table 2) and allows problem drinking that leads to medical problems to be diagnosed in the absence of dependence. DSM–III–R, DSM–IV, and ICD10 cover similar content for dependence (table ...

  7. Low-to-moderate use of alcohol may facilitate socialization, as it reduces anxiety and has a disinhibiting effect on social behaviors. Compared to other drugs of abuse, relatively large amounts of alcohol are required to produce physiological effects.