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3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, also known as MTT, is a compound used in colorimetric assays for cancer drug screening. It is converted by mitochondrial enzymes to formazan, a purple dye, allowing the detection of live cells based on the amount of formazan produced.
- Cell Viability
Cell survival is a complex process, in particular the study...
- Cell Viability
MTT is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble MTT to an insoluble purple formazan. The formazan is then solubilized, concentration determined by optical density.
7 Μαΐ 2021 · 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl diphenyltetrazolium bromide | C30H26BrN5S | CID 129880506 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
14 Οκτ 2021 · 3'- (4,5-Dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide | C18H16BrN5S | CID 22288011 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
3- (4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction is one of the most frequently used methods for measuring cell proliferation and neural cytotoxicity. It is widely assumed that MTT is reduced by active mitochondria in living cells.
3- (4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide bromide | C36H36Br2N10S2 | CID 129826086 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
15 Ιαν 1999 · A colorimetric method for the determination of cell densities using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] proved to be more accurate and timesaving than conventional hemocytometer counting.
