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Intrapleural pressure depends on the ventilation phase, atmospheric pressure, and the volume of the intrapleural cavity. [2] At rest, there is a negative intrapleural pressure. This provides a transpulmonary pressure, causing the lungs to expand.
Pleural pressure, or Ppl, is the pressure surrounding the lung, within the pleural space. During quiet breathing, the pleural pressure is negative; that is, it is below atmospheric pressure. The pleura is a thin membrane which invests the lungs and lines the walls of the thoracic cavity.
9 Ιαν 2023 · The direct measurement of pleural pressures during thoracentesis is known as pleural manometry. The indications, technique, and interpretation of pleural pressures during pleural fluid manometry will be reviewed here.
21 Φεβ 2018 · One theory maintains that the pleura serves as an elastic serous membrane to allow changes in lung shape with respiration, whereas others suggest that the slightly negative pleural pressure...
Another study of 57 patients identified 9 with post-thoracentesis pneumothorax. 58 In those with pneumothorax, the most negative pleural pressure during thoracentesis was −10.8 cm H 2 O in patients with an expandable lung and −17.3 cm H 2 O in those with a nonexpandable lung.
A positive pleural biopsy and/or pleural fluid cytology result indicates a malignant effusion. In the cases when the pleural fluid cytology and pleural biopsy are negative, the effusion is termed a paramalignant pleural effusion.
Excessively negative pleural pressure compared to the normal state is present during both inhalation and exhalation, and shifts the balance of Starling forces that are responsible for the production of pleural fluid such that more fluid moves into the pleural space.
