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Prazosin is a well-tolerated generically available medication that has a small but positive evidence base for the treatment of PTSD-associated nightmares. Given the difficulty of treating nightmares, combined with the continued presence of patients with nightmares, prazosin can be an important pharmacologic treatment option.
- High-dose prazosin for the treatment of post-traumatic stress disorder ...
There is evidence to support the notion that prazosin is...
- High-dose prazosin for the treatment of post-traumatic stress disorder ...
4 Οκτ 2024 · Minipress is a blood pressure drug that may help reduce nightmares and sleep disturbances in people with PTSD. Learn how it works, its benefits, risks, and side effects.
18 Οκτ 2023 · Prazosin — Prazosin, an alpha-1 adrenergic receptor antagonist, is the best studied medication for nightmares and has been the preferred first-line pharmacotherapy when medication is deemed necessary .
2 Μαρ 2023 · Prazosin is a medication that can relax smooth muscles and lower blood pressure. It may also help reduce PTSD nightmares, but the evidence is mixed. Learn about the side effects, warnings, and other treatments for PTSD nightmares.
Nightmares, frequently associated with posttraumatic stress disorder and clinically relevant in today’s world of vio-lence, are difficult to treat, with few pharmacologic options. We performed a systematic review to evaluate the evidence for the use of prazosin in the treatment of nightmares.
There is evidence to support the notion that prazosin is effective for PTSD nightmares. However, PTSD-related nightmares often do not resolve completely on a low dose of prazosin. The capacity of prazosin to treat daytime symptoms of PTSD which are distressing to patients has not been well studied.
15 Απρ 2008 · Therapy with prazosin resulted in a reduction in nightmares in patients with both combat- and noncombat-related trauma. A therapeutic benefit occurred with prazosin dosages as low as 1 mg daily, and suppression of nightmare symptoms occurred within one week of prazosin initiation.
