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1 Ιουν 2015 · The measures chosen to assess the impact of the interventions are called the outcome measures in the trial (or the trial endpoints). Such measures should be defined at the time the trial is designed and should be specified in detail in the study protocol.
The primary outcome measure is the outcome that an investigator considers to be the most important among the many outcomes that are to be examined in the study. The primary outcome needs to be defined at the time the study is designed.
An optimal primary outcome is the one for which there is the most existing or plausible evidence of being associated with the exposure of interest or intervention. Including too many primary outcomes can (a) lead to an unfocused research question and study and (b) present problems with interpretation if the treatment effect differed across the ...
10 Απρ 2023 · The primary outcome of medical research is the main outcome measure that the study aims to answer (i.e. based on the primary objective). In an experimental, semi-experimental or observational research study, the primary study outcome is based on and aligned directly with the primary objective.
2.1.1 Primary outcomes. Primary outcomes are the most important outcomes of the study, the ones that determine its design and the study size. They represent the main reason the trial is being conducted.
1 Ιαν 2023 · Outcome variables can either be principal (primary) or secondary. Primary outcome measures are defined in the hypothesis and are a determinant in selecting the sample size. Secondary outcomes are relevant to the research question and help researchers better understand the primary outcome.
An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment.
