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In a case of acute propylene glycol poisoning, neurotoxic symptoms included stupor and repetitive convulsions (Lolin et al. 1988). The study does not specify the amount of propylene glycol that caused neurotoxicity.
Toxic effects include hyperosmolality, increased anion gap metabolic acidosis (due to lactic acidosis), acute kidney injury, and sepsis-like syndrome. Treatment of toxicity includes hemodialysis to effectively remove propylene glycol. Prevention is best achieved by limiting the dose of propylene glycol infused.
Propylene glycol is a common additive for foods and medications, but it can be toxic when ingested or applied in large amounts. Learn about the sources of exposure, the biological fate, and the toxicological effects of propylene glycol, such as metabolic acidosis, kidney injury, and arrhythmias.
Little quantitative information on propylene glycol levels in various human tissues and body fluids of a control population, populations near hazardous waste sites, or occupationally exposed groups in the United States is available. Most information is available for oral exposures (Yu et al. 1985).
17 Ιαν 2018 · Poisonings by the toxic alcohols (methanol, ethylene glycol, isopropanol, diethylene glycol, and propylene glycol) can cause cellular dysfunction and death, 1 but symptoms may be...
Learn about the symptoms, causes, and treatment of ethylene glycol and propylene glycol poisoning, which can be fatal if not treated quickly. Find more information and resources from the Agency for Toxic Substances and Disease Registry.
Propylene glycol is a clear liquid used in antifreeze and food. It is generally safe, but can increase acid in the body with large amounts. Learn more about its uses, exposure, and health effects.
