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The oral LD50 of propylene glycol in dogs is ~9 mL/kg. In cats, ingestion of a diet containing 6%–12% propylene glycol can result in Heinz body formation and decreased RBC survival. Treatment of propylene glycol toxicosis is largely supportive—the use of alcohol dehydrogenase inhibitors is not indicated.
The oral LD50 of propylene glycol in dogs is ~9 mL/kg. In cats, ingestion of a diet containing 6%–12% propylene glycol can result in Heinz body formation and decreased RBC survival. Treatment of propylene glycol toxicosis is largely supportive—the use of alcohol dehydrogenase inhibitors is not indicated.
Propylene glycol poisoning in dogs is caused by ingesting propylene glycol. Propylene glycol is a common ingredient in antifreeze, lubricants, and products of plasticity.
1 Απρ 2015 · What if a dog does ingest a toxic amount of propylene glycol? > Propylene glycol ingested at toxic doses can cause central nervous system depression and lactic acidosis, Brutlag says. The oral median lethal dose (LD50) of propylene glycol in dogs has been reported to be ~9 ml/kg body weight.
Propylene glycol is found in many household products and has a significant toxic risk if ingested by pets. Of note, it is commonly found in ‘pet-safe’ anti-freeze products. While this form of anti-freeze is less toxic than those containing ethylene glycol, these products still pose a risk to pets if ingested.
13 Δεκ 2011 · To the authors' knowledge, this is the first report of documented propylene glycol intoxication in a dog, as well as the first report to describe hemodialysis as treatment for propylene glycol intoxication in a dog.
Objective: To describe the clinical course, treatment, and outcome of a dog with propylene glycol intoxication. Case summary: An adult castrated male Australian cattle dog presented to an emergency clinic for an acute onset of ataxia and disorientation after roaming a construction site unsupervised.