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5 Μαΐ 2022 · The bacterium Y. pestis, the agent that causes plague, can temporarily or permanently block the proventriculus and blood flow from the esophagus to the midgut in fleas by forming a biofilm.
20 Μαρ 2023 · We developed a semiautomated fluorescent image analysis method and used it to monitor and compare colonization of the flea proventriculus by a fully competent flea-blocking Y. pestis strain, a partially competent strain, and a noncompetent strain.
Soon the flea's proventriculus is blocked by a mass of bacteria and it cannot fill its stomach, causing the flea to search for a new host. After biting the host, the blood of an uninfected host mixes with bacteria in the flea's stomach; the flea expels infected blood back into the wound consequently, infecting a new host.
Pla-negative Y. pestis strains are able to block the rat flea Xenopsylla cheopis as well as wild type strains, with the same inverse relationship between blockage rate and ambient temperature, refuting both predictions of the coagulase model (Hinnebusch et al. 1998).
21 Ιαν 2021 · The Yersinia pestis HmsCDE regulatory system is essential for blockage of the oriental rat flea (Xenopsylla cheopis), a classic plague vector. Environ Microbiol. 2015;17:947–59.
15 Δεκ 2023 · Fleas are ectoparasitic blood-sucking insects with the ability to jump, which commonly infest wild and domestic animals (mainly dogs and cats) but also humans. In addition to serious dermatological conditions mainly related to allergic reactions, fleas can be vectors for various pathogens.
the rodents by the bite of an infected flea in which regurgitation of the blood due to obstruction (blocking) of the proventriculus introduces the plague bacilli into the body of the host.
