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  1. 8 Νοε 2021 · Nanopore sequencing is being applied in genome assembly, full-length transcript detection and base modification detection and in more specialized areas, such as rapid clinical diagnoses and...

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      As CRISPR therapies move into clinical testing, David...

    • DNA Sequencing

      Sanger sequencing by replicative synthesis in the presence...

  2. 13 Ιουλ 2023 · NGS can sequence millions of DNA fragments at once, providing detailed information about the structure of genomes, genetic variations, gene activity, and changes in gene behavior. Recent advancements have focused on faster and more accurate sequencing, reduced costs, and improved data analysis.

  3. 4 Οκτ 2024 · Sanger sequencing by replicative synthesis in the presence of dideoxy nucleotide chain terminator monomers has now given way to 'next generation' sequencing by short parallel read...

  4. 9 Μαΐ 2023 · Recently, single-molecule, long-read sequencing has emerged as an essential tool in deciphering genome structure and function, including filling gaps in the human reference genome, measuring...

  5. 2 Ιαν 2021 · The focus of genomics research has recently moved beyond analyzing DNA variation to studying patterns of gene expression in individual cells, a step that has been driven by new methods for...

  6. 10 Μαΐ 2023 · Powered by the latest in DNA sequencing technology, the pangenome collates all 47 unique genomes into a single resource, providing the most detailed picture yet of the code that powers our...

  7. 1 ημέρα πριν · Whole genome sequencing (WGS) has become a gold standard for diagnosing genomic variation. Peripheral blood is a common sample source for the extraction of nucleic acids for Next-Generation Sequencing (NGS) applications. Here, we present an integrated and fully automated device design that uses new concepts of fluid mechanics, heat-mass transfer, and thermodynamics of enzymatic reactions to ...

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