Αποτελέσματα Αναζήτησης
21 Δεκ 2021 · It can occur at any age, but glioblastoma is more common in older adults. The average age of diagnosis is 64. Also known as glioblastoma multiforme, glioblastoma can cause worsening headaches, nausea, vomiting and seizures. Symptoms vary based on the tumor's size, location and rate of growth.
Median overall survival was 9.9 years (95% confidence interval [95% CI] 7.9–11.9). Patients without recurrence experienced longer median survival (not reached) than patients with one or more recurrences (8.92 years) (p < 0.001) and had a high rate (48.8%) of MGMT promoter-unmethylated tumours.
19 Ιουν 2019 · Clinical factors such as age less than 65 years and Karnofsky performance status score (KPS) higher than 70 have been found to be positive prognostic factors, and abnormal baseline Mini-Mental Status Exam score has been shown to be a negative prognostic factor for overall survival for high-grade gliomas. 3-6 However, the previously established p...
6 Σεπ 2024 · In population-based studies, the median survival of patients 65 years of age and older with newly diagnosed glioblastoma is approximately six months [2-5]. Older adults also tend to receive less aggressive therapy, which may influence outcomes [5-8].
1 Ιουν 2023 · Glioblastoma is the most aggressive and common primary brain tumor. Patients usually present with a short clinical history that often includes focal neurological deficits. Historically 1- and 5-year survival of patients with this disease has been low.
15 Ιουν 2017 · The 2-year survival rate of glioblastoma in patients 65 to 74 years of age is only 8.9%, and is 3.2% for patients older than 75. In the United States, the incidence of glioblastoma is 3.2 per 100,000 persons, and the median age at onset is 64 years.
Tumor site was dichotomized into tumor confined to the frontal lobe and at least some tumor outside of the frontal lobe because previous studies have shown a reduced risk of death when the tumor is confined to the frontal lobe. 17,18 Age and KPS were analyzed as continuous measures and were also dichotomized. Age was dichotomized at the median ...
