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  1. 1 Δεκ 2023 · This sophisticated design of a controlling RNA device, localized within the transcribed RNA molecule, undoubtedly represents one of the pinnacles of molecular RNA evolution. As we have seen, there are compelling reasons to believe that many modern signaling pathways emerged in the RNA World.

  2. 11 Νοε 2014 · This paper brings together a wide range of theories and models of RNA evolution and clearly explains the issues from evolutionary theory.

  3. We have seen in this chapter, for example, that a molecule of RNA is the catalyst for the peptidyl transferase reaction that takes place on the ribosome. The unique potential of RNA molecules to act both as information carrier and as catalyst forms the basis of the RNA world hypothesis.

  4. By synthesizing origin of life (OoL) research from its inception to recent findings, with a focus on (i) proof-of-principle prebiotically plausible syntheses and (ii) molecular relics of the ancient RNA World, we present a comprehensive up-to-date description of science's understanding of the OoL and the RNA World hypothesis.

  5. 5 Οκτ 2015 · In addition to its importance for the origin of life, the RNA World is also an ideal model system for studying fundamental issues about evolution. One such issue is the balance between natural selection, which is largely deterministic, and chance events.

  6. 11 Ιουλ 2002 · RNA evolution in the laboratory, which can be viewed as a model of RNA evolution in the RNA world, has been used to obtain many new RNA enzymes. These include RNAs that catalyse nucleotide...

  7. 11 Απρ 2022 · In this paper, we try to answer this question based on the parasitereplicase model (RP model), which divides RNA molecules into enzymes (RNA replicases) capable of catalyzing replication and parasites that do not possess replicase activity but can be replicated by RNA replicases.