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  1. There are 7 ways to get from Detroit to Saint Louis University by plane, bus, train, or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  2. Compare your options: plane, train, bus, car, ferry, bike share, driving and walking directions all in one search. Bus tickets from Detroit to St. Louis start at $43, and the quickest route takes just 10h 15m. Check timetables and book your tickets with Rome2Rio.

  3. Book your Amtrak train and bus tickets today by choosing from over 30 U.S. train routes and 500 destinations in North America.

  4. Check out the route's schedule and choose the best option to suit your plans! What is the distance between Detroit and St Louis? The bus route from Detroit to St Louis covers 533 miles. FlixBus can bring you from Detroit to St Louis in 12 hours 15 minutes. How much is the bus ticket between Detroit and St Louis?

  5. There are 5 ways to get from Saint Louis University to Detroit by plane, train, bus or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

  6. The trip from Detroit to St Louis takes as short as 12 hours 15 minutes and could cost as little as $135.99. The first bus departs at 9:50 am and the last bus departs at 11:25 pm . Greyhound operates 3 bus rides daily between Detroit and St Louis.

  7. Find the best deals on train tickets from Detroit, MI to St Louis, MO. You can compare the best prices from all train lines and book online directly with Wanderu.